Tuesday, 28 January 2014

InterProScan 5 is out

Towards the end of last year, we released InterProScan 5. This represented a complete redesign of the popular InterProScan software that compares protein sequences against different InterPro member database signatures, to classify them into protein families and predict the presence of important domains and sites. The new version of the software is highly flexible, robust and scalable. Multiple output formats are available, including tab-delimited, XML and GFF3, as well as graphical output in HTML and SVG formats (an example of which is given below). You can find more details about InterProScan 5 here and read the paper describing it here.

InterProScan graphical output when searched with UniProt entry B0A027. 
A month or two on from the software release, we think we have ironed out (most of!) the bugs and urge you to give it a go. This is particularly important for InterProScan 4 users; whilst InterProScan 4.8 is still available for download, we are not supporting it any more and so highly recommend that you upgrade. We are also very interested in hearing what you think about the new software, your experiences installing and running it, and what you might be using it for. So drop us a line, using the comments section below.

Alex Mitchell
on behalf of the InterPro team


  1. Hi

    I am working on a 64 bit machine. fingerPrintScan is compiled for 32 bit machines and not working on my machine. I downloaded the source from ftp://ftp.bioinf.man.ac.uk/pub/fingerPRINTScan/program/ , compiled it but now I get a "The Compact database seems to be incorrectly formatted". Do you know where I can get a 64-bit fingerPrintScan that accepts the compact Database? Is it possible and OK to remove fingerPrintScan from interproscan. If yes how should I proceed? Thanks

    1. Hi,
      The latest version of FingerPrintScan is compiled for 64 bit machines. It is available as part of the InterProScan package. See here for download and installation instructions: